IUIs may be an incredibly poor option for some (like those with blocked tubes), making the odds of birth next to zero. On a per birth basis, the picture isn’t quite as clear.On a per cycle basis, IUI is significantly more affordable.Costs range greatly for both an IUI and IVF and depend upon a number of factors.If an IUI is to be successful it most often happens in the first three or four treatment cycles. IUIs generally have a success rate of around 5-20% per cycle.For those under 35, success rates are generally around 50% per treatment. IVF has a much faster time to pregnancy due to it’s higher success rate per cycle.
If a patient has blocked tubes, severe male factor infertility, or a number of other male or female factors, a fertility specialist may recommend jumping straight to in vitro fertilization as IVF works around substantially more infertility causing issues and an IUI.
There are many diagnoses that are contraindicative of IUI. IUI is less invasive, so if diagnosis allows, it is generally tried before proceeding to the more invasive IVF procedure. IVF requires “surgery” under anesthesia, whereas an IUI does not. Proper monitoring, medication choice and dosage, and general care greatly reduce the risks and side effects. Both procedures are safe, and the risks are minimal. Elective: IVF can also be used for elective reasons like sex selection. Egg Quality and quantity: The large dosages of medications mature a large number of eggs, mature eggs, are high-quality eggs. Miscarriage: Both genetic testing and reproductive immunology can be used alongside IVF which may reduce the odds of miscarriage for some. Uterine: Numerous medications can be given to optimize uterine receptivity and the timing of an embryo transfer. Sperm: With ICSI – a technique that directly injects sperm into the egg, you literally only need one healthy sperm. Tubal issues: eggs are removed from the ovaries and the embryos are put back directly into the uterus completely bypassing the tubes. Ovulation: eggs are retrieved before ovulation. IUI can increase the number of sperm that make it to the fallopian tube by 1000x. Sperm Quality: An IUI puts sperm much closer to its target (the egg). Egg quality and ovulation: Medications are given to help grow and ovulate one or two mature eggs (some women may not ovulate otherwise). An IUI helps beat infertility in two primary ways. After growing for a few days in the lab, an embryo is transferred back into the woman’s uterus. The eggs are then fertilized outside of the body in a lab. Once many eggs have developed, a procedure takes place where the eggs are removed from the ovaries. IVF: During IVF, medications are usually taken for around 10 days to grow a large number of eggs. This greatly increases the number of sperm at the junction of the uterus and fallopian tubes, the distance they have to swim to meet the egg, and thus increases the chances of natural conception for many people. Around day 14 of a woman’s cycle, the insemination takes place which deposits sperm inside the uterus. IUI: An IUI can be done with no medications or a number of different medications to help develop and ovulate one or two eggs. While this may sound like a relatively minor difference, it leads to leads to a large number of noteworthy differences. The eggs are removed from the ovaries, fertilized and developed in a lab for a number of days, and subsequently put back into the uterus as an early-stage embryo. Ideally, they develop around 15 mature eggs. In IVF, a woman is given more medications to develop lots of eggs. Sperm are deposited within the uterus, which gives the sperm a head start but still requires natural fertilization to take place. With an IUI, a woman is only supposed to develop one or two eggs. The main difference between IUI and IVF is the number of eggs the female produced and the place of fertilization. We start things off with a high-level overview, then jump into the different types of each treatment, discuss treatment details, key decisions within each treatment, success rates, cost comparisons, risks, and who each treatment might be a good fit for. 
In it, we discuss everything you need to know about IUI and IVF.
While it’s always recommended to consult with a medical provider before making any treatment decisions, this article serves as a great jumping point for those looking to get pregnant using assisted reproductive technologies (ART). But how do you know if IUI or IVF is the right treatment option for you? One of the first things people should do when exploring fertility treatment options is to compare intrauterine inseminations (IUI) and in vitro fertilization (IVF) as they are two of the most common and effective fertility treatments.
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